Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fixAElectron transfer flavoprotein, beta subunit; Identified by similarity to SP:P53577; match to protein family HMM PF01012. (280 aa)    
Predicted Functional Partners:
fixB
Electron transfer flavoprotein, alpha subunit; Identified by similarity to SP:P26483; match to protein family HMM PF00766; match to protein family HMM PF01012.
 0.999
fixX
Ferredoxin-like protein; Could be a 3Fe-4S cluster-containing protein.
 
 0.997
fixC
fixC protein; Part of an electron transfer system. Belongs to the ETF-QO/FixC family.
 
 
 0.976
AFE_3010
Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.
  
 
 0.871
AFE_2211
Oxidoreductase, FAD/FMN-binding; Identified by match to protein family HMM PF00724.
  
 
 0.828
AFE_0004
Conserved hypothetical protein; Identified by similarity to GB:AAO90130.1.
  
 
 0.755
AFE_1769
Oxidoreductase, FAD-binding, putative; Identified by similarity to GB:AAQ61895.1; match to protein family HMM PF01565; match to protein family HMM PF02754; match to protein family HMM PF02913.
  
 
 0.733
AFE_0788
Non-heme halogenase, putative; Identified by similarity to GB:AAK81830.1; match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM PF04820.
  
 
 0.685
AFE_2544
Identified by match to protein family HMM PF01494; match to protein family HMM PF05834; match to protein family HMM TIGR02032.
  
 
 0.685
gltD
Glutamate synthase, small subunit; Identified by similarity to SP:P09832; match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01318.
   
   0.677
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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