Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AFE_1483TonB-dependent receptor; Identified by match to protein family HMM PF00593. (754 aa)    
Predicted Functional Partners:
AFE_1489
Iron compound ABC transporter, periplasmic iron-binding protein, putative; Identified by match to protein family HMM PF01497.
 
    0.837
AFE_1494
Iron compound ABC transporter, periplasmic iron-binding protein, putative; Identified by match to protein family HMM PF01497.
 
    0.803
AFE_1491
Iron compound ABC transporter, ATP-binding protein, putative; Identified by similarity to SP:P15031; match to protein family HMM PF00005.
 
  
 0.758
AFE_1482
Conserved domain protein; Identified by similarity to GB:AAN51174.1.
       0.757
AFE_1487
Identified by match to protein family HMM PF03544; match to protein family HMM TIGR01352.
 
   0.721
AFE_1490
ABC transporter, permease protein, FecCD family; Identified by match to protein family HMM PF01032; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
  
 0.708
AFE_1486
Biopolymer transport protein, ExbD/TolR family; Identified by match to protein family HMM PF02472.
 
    0.695
AFE_1495
ABC transporter, permease protein, FecCD family; Identified by match to protein family HMM PF01032; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
  
 0.636
AFE_1485
MotA/TolQ/ExbB proton channel family protein; Identified by match to protein family HMM PF01618.
 
    0.625
AFE_1484
Conserved hypothetical protein; Identified by similarity to GB:AAM72768.1.
 
    
0.563
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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