Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_1501Conserved domain protein; Identified by similarity to GB:AAN66836.1; match to protein family HMM TIGR02605. (76 aa)    
Predicted Functional Partners:
AFE_1510
Conserved hypothetical protein; Identified by similarity to GB:AAB66329.1.
 
     0.828
AFE_1513
Conserved hypothetical protein; Identified by similarity to GB:AAK51500.1; match to protein family HMM PF05082.
 
    0.784
AFE_1543
Conserved hypothetical protein; Identified by similarity to GB:AAF61911.1.
  
    0.777
AFE_1534
Leucine rich repeat protein; Identified by match to protein family HMM PF01816.
  
    0.770
AFE_1523
Response regulator.
  
     0.759
AFE_1502
Ankyrin repeat protein/rhodanese-like domain protein; Identified by match to protein family HMM PF00023; match to protein family HMM PF00581.
 
     0.744
AFE_1536
NifZ domain protein.
  
     0.731
AFE_1533
Conserved hypothetical protein; Identified by similarity to SP:P23177.
  
     0.728
AFE_1503
Nitroreductase, putative.
 
     0.725
AFE_1476
Conserved hypothetical protein; Identified by similarity to GB:AAA64729.1.
  
     0.713
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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