Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nifWnifW protein, putative; May protect the nitrogenase Fe-Mo protein from oxidative damage; Belongs to the NifW family. (110 aa)    
Predicted Functional Partners:
nifK
Nitrogenase molybdenum-iron protein, beta subunit; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation; Belongs to the NifD/NifK/NifE/NifN family.
 
  
 0.933
nifX
Nitrogen fixation protein NifX; Identified by similarity to SP:P19078; match to protein family HMM PF02579; match to protein family HMM TIGR02663.
 
  
 0.924
AFE_1511
Nitrogen fixation protein NifQ; Identified by match to protein family HMM PF04891.
 
  
 0.900
nifN
Nitrogenase molybdenum-iron cofactor biosynthesis protein NifN; Identified by match to protein family HMM PF00148; match to protein family HMM TIGR01285; Belongs to the NifD/NifK/NifE/NifN family.
 
  
 0.899
nifE
Nitrogenase MoFe cofactor biosynthesis protein NifE; Identified by match to protein family HMM PF00148; match to protein family HMM TIGR01283; Belongs to the NifD/NifK/NifE/NifN family.
 
  
 0.893
nifB
Nitrogenase cofactor biosynthesis protein NifB; Identified by match to protein family HMM PF02579; match to protein family HMM PF04055; match to protein family HMM TIGR01290.
 
  
 0.892
nifV
Homocitrate synthase; Identified by similarity to SP:Q44290; match to protein family HMM PF00682; match to protein family HMM TIGR02660; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
  
 0.890
nifD
Nitrogenase molybdenum-iron protein, alpha subunit; Identified by similarity to SP:P06121; match to protein family HMM PF00148; match to protein family HMM TIGR01282; match to protein family HMM TIGR01862.
 
  
 0.886
AFE_1514
Conserved hypothetical protein; Identified by similarity to GB:BAC47013.1; match to protein family HMM PF03270; match to protein family HMM TIGR02935.
 
  
 0.874
AFE_1535
NifZ domain protein; Identified by match to protein family HMM PF04319.
 
   
 0.862
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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