Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AFE_1533Conserved hypothetical protein; Identified by similarity to SP:P23177. (169 aa)    
Predicted Functional Partners:
AFE_1534
Leucine rich repeat protein; Identified by match to protein family HMM PF01816.
 
     0.952
AFE_1536
NifZ domain protein.
 
     0.952
AFE_1535
NifZ domain protein; Identified by match to protein family HMM PF04319.
 
 
   0.946
AFE_1539
Conserved hypothetical protein; Identified by similarity to GB:AAA64714.1.
 
     0.938
AFE_1538
Nitrogen fixation protein, putative; Identified by similarity to SP:P09427; match to protein family HMM PF06988; match to protein family HMM TIGR02934.
 
     0.923
AFE_1543
Conserved hypothetical protein; Identified by similarity to GB:AAF61911.1.
 
     0.908
AFE_1499
ATPase, AAA family; Identified by match to protein family HMM PF00004.
  
 
 0.873
AFE_1502
Ankyrin repeat protein/rhodanese-like domain protein; Identified by match to protein family HMM PF00023; match to protein family HMM PF00581.
 
 0.841
AFE_1541
Ferredoxin, putative; Identified by similarity to SP:P44428; match to protein family HMM PF00111.
 
     0.822
AFE_1540
Aminotransferase, DegT/DnrJ/EryC1/StrS family; Identified by match to protein family HMM PF01041; Belongs to the DegT/DnrJ/EryC1 family.
 
     0.812
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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