STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFE_1540Aminotransferase, DegT/DnrJ/EryC1/StrS family; Identified by match to protein family HMM PF01041; Belongs to the DegT/DnrJ/EryC1 family. (380 aa)    
Predicted Functional Partners:
AFE_3291
Identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993.
  
 
 0.915
gmd-1
GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
  
 
 0.911
gmd-2
GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
  
 
 0.911
AFE_1457
Oxidoreductase, NAD-binding; Identified by match to protein family HMM PF01408; match to protein family HMM PF02894.
  
 0.871
AFE_1536
NifZ domain protein.
 
     0.828
AFE_1539
Conserved hypothetical protein; Identified by similarity to GB:AAA64714.1.
 
     0.826
AFE_1534
Leucine rich repeat protein; Identified by match to protein family HMM PF01816.
 
     0.823
AFE_1538
Nitrogen fixation protein, putative; Identified by similarity to SP:P09427; match to protein family HMM PF06988; match to protein family HMM TIGR02934.
 
     0.821
AFE_1533
Conserved hypothetical protein; Identified by similarity to SP:P23177.
 
     0.813
rfbB
dTDP-glucose 4,6-dehydratase; Identified by similarity to SP:P55295; match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01181; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
 
  
 0.806
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.