Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AFE_1541Ferredoxin, putative; Identified by similarity to SP:P44428; match to protein family HMM PF00111. (101 aa)    
Predicted Functional Partners:
fdx
Ferredoxin, 2Fe-2S; Identified by similarity to SP:P25528; match to protein family HMM PF00111; match to protein family HMM TIGR02007.
 
  
  0.976
AFE_0859
Pyridine nucleotide-disulfide oxidoreductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992.
     
  0.900
AFE_1543
Conserved hypothetical protein; Identified by similarity to GB:AAF61911.1.
 
     0.851
AFE_1539
Conserved hypothetical protein; Identified by similarity to GB:AAA64714.1.
 
     0.849
AFE_1536
NifZ domain protein.
 
     0.847
AFE_1533
Conserved hypothetical protein; Identified by similarity to SP:P23177.
 
     0.822
AFE_1534
Leucine rich repeat protein; Identified by match to protein family HMM PF01816.
 
     0.801
AFE_1542
Hypothetical protein; Identified by glimmer; putative.
       0.775
hscB
Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.
  
     0.755
AFE_0679
Conserved hypothetical protein; Identified by similarity to SP:Q51384; match to protein family HMM PF04384; match to protein family HMM TIGR03412.
  
     0.737
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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