Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFE_1563Repressor protein CI homolog. (164 aa)    
Predicted Functional Partners:
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.925
AFE_1561
Hypothetical protein; Identified by glimmer; putative.
       0.773
AFE_1562
Hypothetical protein; Identified by glimmer; putative.
       0.773
AFE_1564
Prophage Afe02, transcriptional regulator, Cro family.
  
    0.559
AFE_1869
Cell division inhibitor, putative; Identified by similarity to SP:P08845.
  
  
 0.464
AFE_1568
Methyltransferase, putative; Identified by match to protein family HMM PF02086.
       0.460
AFE_1565
Hypothetical protein; Identified by glimmer; putative.
       0.445
AFE_1751
umuC protein; Identified by match to protein family HMM PF00817.
  
 
 0.444
AFE_1870
Conserved hypothetical protein; Identified by similarity to GB:AAM40399.1.
  
 
 0.444
dinB
DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
  
 
 0.444
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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