Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_1568Methyltransferase, putative; Identified by match to protein family HMM PF02086. (296 aa)    
Predicted Functional Partners:
AFE_1566
DNA replication protein DnaC, putative; Identified by similarity to SP:P07905; match to protein family HMM PF01695.
 
    0.816
AFE_1567
Hypothetical protein; Identified by glimmer; putative.
       0.773
AFE_1565
Hypothetical protein; Identified by glimmer; putative.
       0.769
AFE_1564
Prophage Afe02, transcriptional regulator, Cro family.
       0.598
ssb-2
Single-strand binding protein; Identified by match to protein family HMM PF00436; match to protein family HMM TIGR00621.
       0.595
AFE_1221
Modification methylase, putative; Identified by similarity to SP:P11409.
 
  
 0.556
AFE_2430
Conserved hypothetical protein; Identified by similarity to GB:BAB47830.1; match to protein family HMM PF01987.
  
     0.529
AFE_1615
DNA primase TraC; Identified by similarity to SP:P27189; match to protein family HMM PF08401.
 
     0.528
AFE_3220
Hypothetical protein; Identified by glimmer; putative.
  
    0.526
AFE_1855
Membrane protein, putative; Identified by match to protein family HMM PF07690.
  
     0.525
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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