Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_1577Type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384. (484 aa)    
Predicted Functional Partners:
AFE_1575
Type I restriction-modification system, R subunit; Identified by similarity to SP:P08956; match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM PF08463.
 
 
 0.989
AFE_1576
Type I restriction-modification system, S subunit; Identified by match to protein family HMM PF01420.
 
   0.975
AFE_0686
Type I restriction-modification system, S subunit, putative; Identified by similarity to SP:P19704; match to protein family HMM PF01420.
 
 
 0.888
AFE_0683
Type I restriction-modification system, R subunit; Identified by similarity to SP:Q47281; match to protein family HMM PF00271; match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM PF08463.
 
 
 0.853
AFE_2378
Type I restriction-modification system, S subunit; Identified by match to protein family HMM PF01420.
  
 
 0.774
AFE_0829
Type I restriction-modification system, S subunit; Identified by match to protein family HMM PF01420.
 
   0.711
AFE_1636
Hypothetical protein; Identified by glimmer; putative.
      
 0.707
AFE_1651
Identified by similarity to SP:O34969; match to protein family HMM PF03446; match to protein family HMM PF03807.
      
 0.707
AFE_2393
ISAfe5, transposase orfA; Identified by similarity to GB:AAB81643.1.
      
 0.707
AFE_2312
Identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00879; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
   
  
 0.610
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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