Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_1659Hypothetical protein; Identified by glimmer; putative. (342 aa)    
Predicted Functional Partners:
isp1
Membrane protein, putative.
  
     0.770
AFE_2529
Hypothetical protein; Identified by glimmer; putative.
  
     0.750
AFE_0743
Conserved domain protein.
  
     0.745
isp2
Iron-sulfur cluster-binding protein; Identified by match to protein family HMM PF00037; match to protein family HMM PF02754.
  
     0.675
AFE_1681
Conserved hypothetical protein; Identified by similarity to GB:CAE21373.1.
  
     0.629
AFE_1667
Transketolase pyridine binding domain protein; Identified by match to protein family HMM PF02779.
 
     0.590
AFE_1666
Conserved hypothetical protein; Identified by similarity to PIR:AG2237.
 
     0.555
hynH
Hydrogenase expression protein, putative.
  
     0.538
AFE_2556
Conserved hypothetical protein; Identified by similarity to GB:AAM72097.1.
  
     0.531
sqr
Sulfide quinone reductase, putative; Identified by similarity to GB:AAF72963.1; match to protein family HMM PF07992.
  
     0.528
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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