STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glcFGlycolate oxidase, iron-sulfur subunit; Identified by similarity to SP:P52074; match to protein family HMM PF00037; match to protein family HMM PF02754. (416 aa)    
Predicted Functional Partners:
glcE
Glycolate oxidase, subunit GlcE; Identified by similarity to SP:P52073; match to protein family HMM PF01565.
 
 
 0.995
glcD
Glycolate oxidase, subunit GlcD; Identified by match to protein family HMM PF01565; match to protein family HMM PF02913.
 
 
 0.995
AFE_2218
HAD-superfamily hydrolase, subfamily IA; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549.
     
  0.900
gph-2
Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
     
  0.900
AFE_0778
Conserved domain protein.
     
  0.800
AFE_1666
Conserved hypothetical protein; Identified by similarity to PIR:AG2237.
       0.767
AFE_1667
Transketolase pyridine binding domain protein; Identified by match to protein family HMM PF02779.
       0.730
AFE_1668
Transcriptional regulator, IclR family; Identified by match to protein family HMM PF01614; match to protein family HMM PF09339.
 
    0.711
AFE_0140
Oxidase, FAD-binding; Identified by match to protein family HMM PF01565; match to protein family HMM PF02913.
 
  
 0.632
AFE_1662
NADH dehydrogenase, putative; Identified by match to protein family HMM PF00361.
  
    0.468
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.