Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFE_1667Transketolase pyridine binding domain protein; Identified by match to protein family HMM PF02779. (722 aa)    
Predicted Functional Partners:
AFE_1666
Conserved hypothetical protein; Identified by similarity to PIR:AG2237.
 
     0.944
glcE
Glycolate oxidase, subunit GlcE; Identified by similarity to SP:P52073; match to protein family HMM PF01565.
       0.743
glcD
Glycolate oxidase, subunit GlcD; Identified by match to protein family HMM PF01565; match to protein family HMM PF02913.
       0.743
glcF
Glycolate oxidase, iron-sulfur subunit; Identified by similarity to SP:P52074; match to protein family HMM PF00037; match to protein family HMM PF02754.
       0.730
AFE_1668
Transcriptional regulator, IclR family; Identified by match to protein family HMM PF01614; match to protein family HMM PF09339.
 
     0.621
AFE_1659
Hypothetical protein; Identified by glimmer; putative.
 
     0.590
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
    
 0.571
AFE_1347
Hypothetical protein; Identified by glimmer; putative.
  
     0.559
rpe
Ribulose-phosphate 3-epimerase; Identified by match to protein family HMM PF00834; match to protein family HMM TIGR01163; Belongs to the ribulose-phosphate 3-epimerase family.
    
 0.557
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
 
  
 0.540
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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