Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_1677Von Willebrand factor type A domain protein; Identified by match to protein family HMM PF00092. (783 aa)    
Predicted Functional Partners:
p30
P30 protein; Identified by similarity to GB:BAA76361.1; match to protein family HMM PF07728; match to protein family HMM PF08406.
 
 
 0.990
cbbQ-1
CbbQ protein; Identified by similarity to GB:BAA76361.1; match to protein family HMM PF07728; match to protein family HMM PF08406.
 
 
 0.930
cbbQ-2
CbbQ protein; Identified by similarity to GB:BAA76361.1; match to protein family HMM PF07728; match to protein family HMM PF08406.
 
 
 0.911
AFE_2536
CbbQ/NirQ/NorQ/GpvN family protein; Identified by similarity to SP:Q02441; similarity to SP:Q51858; match to protein family HMM PF07728; match to protein family HMM PF08406.
 
 
 0.873
AFE_1681
Conserved hypothetical protein; Identified by similarity to GB:CAE21373.1.
 
     0.788
cbbS-2
Ribulose bisphosphate carboxylase, small subunit; Identified by match to protein family HMM PF00101.
 
   
 0.746
AFE_1680
Conserved hypothetical protein; Identified by similarity to GB:AAB36936.1; match to protein family HMM PF01656.
 
     0.744
cbbS-1
Ribulose bisphosphate carboxylase, small subunit; Identified by match to protein family HMM PF00101.
 
   
 0.706
cab2
Carboxysome shell carbonic anhydrase; Identified by similarity to GB:AAD30511.1; match to protein family HMM PF08936; match to protein family HMM TIGR02701.
 
   
 0.668
AFE_1679
Conserved hypothetical protein; Identified by similarity to GB:CAB45259.1.
       0.652
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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