Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AFE_1707Sensory box-containing diguanylate cyclase, putative; Identified by match to protein family HMM PF00563; match to protein family HMM PF00989; match to protein family HMM PF00990; match to protein family HMM PF01590; match to protein family HMM PF08447; match to protein family HMM PF08448; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254. (1057 aa)    
Predicted Functional Partners:
AFE_1595
Hypothetical protein; Identified by glimmer; putative.
 
 
 0.918
AFE_1710
Hypothetical protein; Identified by glimmer; putative.
  
 
 0.874
AFE_1229
EAL domain protein; Identified by match to protein family HMM PF00563.
 
 
 0.855
AFE_1725
Sensory box-containing diguanylate cyclase, putative; Identified by match to protein family HMM PF00563; match to protein family HMM PF00989; match to protein family HMM PF00990; match to protein family HMM PF08448; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254.
 
 
 
0.736
AFE_3057
Sensory box-containing diguanylate cyclase, putative; Identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM PF01590; match to protein family HMM PF08447; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254.
 
 
 
0.686
nifA
Nif-specific regulatory protein; Identified by match to protein family HMM PF00158; match to protein family HMM PF01590; match to protein family HMM PF02954; match to protein family HMM PF07728; match to protein family HMM TIGR01817.
   
 
 0.577
AFE_1712
Diguanylate cyclase, putative; Identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254.
 
 
0.549
AFE_1997
Autoinducer-binding transcriptional regulator, LuxR family; Identified by match to protein family HMM PF00196; match to protein family HMM PF03472.
  
 
 0.529
kdpD
Sensor histidine kinase KdpD; Identified by similarity to SP:P21865; match to protein family HMM PF00512; match to protein family HMM PF00582; match to protein family HMM PF02518; match to protein family HMM PF02702.
  
 
 0.480
AFE_3030
Sugar isomerase, KpsF/GutQ family; Identified by similarity to SP:P45395; match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393; Belongs to the SIS family. GutQ/KpsF subfamily.
     
 0.434
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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