Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_1733Conserved hypothetical protein; Identified by similarity to PIR:E85734; match to protein family HMM PF03681. (147 aa)    
Predicted Functional Partners:
AFE_1732
Hypothetical protein; Identified by glimmer; putative.
   
 
 0.957
AFE_1734
Conserved hypothetical protein; Identified by similarity to PIR:G82661; match to protein family HMM TIGR02684.
 
     0.581
AFE_3189
Conserved domain protein; Identified by similarity to GB:CAD18424.1.
  
     0.524
dinJ
DNA-damage-inducible protein J; Identified by similarity to SP:Q47150; match to protein family HMM PF04221; match to protein family HMM TIGR02384.
 
  
 0.496
AFE_0274
Disulfide bond formation protein B, putative; Identified by similarity to SP:P30018.
  
     0.462
polI
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.445
AFE_1731
Conjugal transfer protein TraB, putative; Identified by similarity to SP:Q44351.
       0.435
AFE_0168
Hypothetical protein; Identified by glimmer; putative.
  
     0.429
AFE_3220
Hypothetical protein; Identified by glimmer; putative.
  
     0.428
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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