Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_1763Glycosyl transferase, group 1; Identified by match to protein family HMM PF00534. (402 aa)    
Predicted Functional Partners:
AFE_1354
Glycosyl transferase, group 1 family protein; Identified by match to protein family HMM PF00534.
  
     0.614
AFE_1762
Conserved hypothetical protein; Identified by similarity to SP:Q9F2U7.
       0.610
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
  
   0.466
mtfA
Mannosyltransferase; Identified by similarity to GB:AAF04384.1; match to protein family HMM PF00534.
  
     0.452
AFE_1761
Conserved hypothetical protein; Identified by similarity to GB:AAQ60975.1.
       0.452
AFE_2082
Identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02402.
   
  0.435
glgB
1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
   
  0.435
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
Server load: low (30%) [HD]