Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Experiments
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[Homology]
Score
AFE_1767Exodeoxyribonuclease X, putative; Identified by similarity to SP:P76281; match to protein family HMM PF00929. (220 aa)    
Predicted Functional Partners:
AFE_1765
Hypothetical protein; Identified by glimmer; putative.
       0.773
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 
 
 0.655
AFE_3220
Hypothetical protein; Identified by glimmer; putative.
  
     0.620
AFE_1497
Conserved hypothetical protein; Identified by match to protein family HMM PF03573.
  
     0.610
AFE_1695
Conjugal transfer protein; Identified by similarity to SP:P54915; match to protein family HMM PF03524.
  
     0.594
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
    
 
 0.581
AFE_1798
Membrane protein, putative.
  
     0.567
AFE_1615
DNA primase TraC; Identified by similarity to SP:P27189; match to protein family HMM PF08401.
  
     0.562
AFE_1991
Conserved hypothetical protein; Identified by similarity to GB:BAC50343.1; match to protein family HMM PF03573.
  
     0.561
AFE_1698
Conjugal transfer -like protein; Identified by match to protein family HMM PF01464.
 
     0.560
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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