Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
AFE_1769Oxidoreductase, FAD-binding, putative; Identified by similarity to GB:AAQ61895.1; match to protein family HMM PF01565; match to protein family HMM PF02754; match to protein family HMM PF02913. (1277 aa)    
Predicted Functional Partners:
AFE_1772
Deoxyguanosine kinase/deoxyadenosine kinase, putative; Identified by similarity to SP:Q59483; similarity to SP:Q59484.
     
 0.806
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
       0.805
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
       0.805
fixA
Electron transfer flavoprotein, beta subunit; Identified by similarity to SP:P53577; match to protein family HMM PF01012.
  
 
 0.733
fixB
Electron transfer flavoprotein, alpha subunit; Identified by similarity to SP:P26483; match to protein family HMM PF00766; match to protein family HMM PF01012.
  
 
 0.731
resB
Cytochrome c-type biogenesis protein ResB; Identified by match to protein family HMM PF05140.
  
     0.674
AFE_3120
Membrane protein, putative.
  
     0.668
AFE_2675
Conserved hypothetical protein; Identified by similarity to GB:CAD84648.1.
  
     0.644
AFE_3010
Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.
  
 
 0.570
resC
Cytochrome c-type biogenesis protein ResC; Identified by match to protein family HMM PF01578; match to protein family HMM TIGR03144.
 
    0.552
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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