Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFE_1779Plasmid stability protein, putative; Identified by similarity to SP:P55510. (84 aa)    
Predicted Functional Partners:
vapC-5
Plasmid stability protein, putative; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
 
 
 
 0.983
vapC-3
Plasmid stability protein, putative; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
 
 
 
 0.925
AFE_1781
Transcriptional regulator, AbrB family; Identified by match to protein family HMM PF04014; match to protein family HMM TIGR01439.
       0.723
AFE_1361
Plasmid stability protein, putative; Identified by similarity to SP:P55510.
  
     0.593
dinJ
DNA-damage-inducible protein J; Identified by similarity to SP:Q47150; match to protein family HMM PF04221; match to protein family HMM TIGR02384.
  
   
 0.489
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
       0.459
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
       0.459
AFE_0094
Prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
  
     0.450
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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