Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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vapC-5Plasmid stability protein, putative; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (139 aa)    
Predicted Functional Partners:
AFE_1779
Plasmid stability protein, putative; Identified by similarity to SP:P55510.
 
 
 
 0.983
AFE_1361
Plasmid stability protein, putative; Identified by similarity to SP:P55510.
 
 
 
 0.849
AFE_1781
Transcriptional regulator, AbrB family; Identified by match to protein family HMM PF04014; match to protein family HMM TIGR01439.
       0.725
AFE_0094
Prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
 
     0.546
AFE_2771
SpoVT/AbrB like domain protein.
 
 
 0.501
AFE_2130
Virulence-associated protein, putative; Identified by similarity to SP:Q05459.
 
 
 0.499
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
       0.459
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
       0.459
AFE_0477
Virulence protein, putative; Identified by similarity to SP:Q05459; match to protein family HMM PF04014.
  
 
 0.433
AFE_1579
Conserved hypothetical protein; Identified by similarity to GB:AAK52344.1.
  
   0.401
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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