Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_1787Identified by match to protein family HMM PF01300; match to protein family HMM TIGR00057; Belongs to the SUA5 family. (211 aa)    
Predicted Functional Partners:
AFE_1788
Membrane-associated zinc metalloprotease, putative; Identified by similarity to GB:CAD85637.1; match to protein family HMM PF02163.
  
    0.648
trpS
tryptophanyl-tRNA synthetase; Identified by similarity to GB:AAA92300.1; match to protein family HMM PF00579; match to protein family HMM TIGR00233; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
    0.644
scpA
Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
       0.644
scpB
Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
       0.644
AFE_2516
Conserved hypothetical protein; Identified by match to protein family HMM PF00814.
 
  
 0.633
gcp
O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
  
 0.603
AFE_1926
Conserved hypothetical protein TIGR00150; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150.
    
 0.568
AFE_1786
Conserved hypothetical protein; Identified by similarity to GB:CAD16844.1.
       0.529
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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