STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFE_1792Sulfide-quinone reductase, putative; Catalyzes the oxidation of hydrogen sulfide, with the help of a quinone. Consecutive reaction cycles lead to the accumulation of a polysulfide product on the active site Cys residues; these products are released when they exceed a critical length, typically as cyclooctasulfur; Belongs to the SQRD family. (434 aa)    
Predicted Functional Partners:
sqr
Sulfide quinone reductase, putative; Identified by similarity to GB:AAF72963.1; match to protein family HMM PF07992.
  
  
 
0.927
AFE_2601
Pyridine nucleotide-disulfide oxidoreductase; Identified by similarity to SP:Q9R112; match to protein family HMM PF07992.
 
 
 0.919
cysI
Sulfite reductase (NADPH) hemoprotein beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
     
 0.917
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
   
  0.907
hoxF
[NiFe] hydrogenase, beta subunit, putative; Identified by similarity to GB:BAC00528.1; match to protein family HMM PF00037.
   
 
  0.901
hoxH
[NiFe] hydrogenase, alpha subunit, putative; Identified by similarity to GB:BAC00531.1; match to protein family HMM PF00374.
     
  0.900
hoxY
[NiFe] hydrogenase, delta subunit, putative; Identified by similarity to GB:BAC00530.1; match to protein family HMM PF01058.
     
  0.900
cysJ
Sulfite reductase (NADPH) flavoprotein, alpha component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
     
 0.900
AFE_2366
Transporter, AcrB/AcrD/AcrF family; Identified by match to protein family HMM PF00873; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
     0.533
rluB
Ribosomal large subunit pseudouridine synthase B; Identified by similarity to SP:P37765; match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; Belongs to the pseudouridine synthase RsuA family.
       0.512
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.