Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFE_1827Membrane-bound lytic murein transglycosylase B, putative; Identified by similarity to SP:P41052. (408 aa)    
Predicted Functional Partners:
AFE_1828
Lipoprotein, NLP/P60 family; Identified by match to protein family HMM PF00877.
     
 0.789
ubiG
3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
 
     0.637
gph-1
Phosphoglycolate phosphatase; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01449; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549.
 
    0.619
secB
Preprotein translocase, SecB subunit; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
  
     0.591
AFE_1826
Identified by match to protein family HMM PF01979; match to protein family HMM PF07969.
       0.576
AFE_1957
Conserved hypothetical protein; Identified by similarity to GB:AAN68501.1; match to protein family HMM PF04357.
  
     0.572
lptD
Organic solvent tolerance protein, putative; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family.
 
     0.564
rlpA
Rare lipoprotein A, putative; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
 
   
 0.559
pepN
Identified by similarity to SP:P04825; match to protein family HMM PF01433; match to protein family HMM TIGR02414.
  
     0.549
AFE_1958
Outer membrane protein, OMP85 family; Identified by match to protein family HMM PF01103; match to protein family HMM PF07244.
  
     0.502
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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