Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AFE_1828Lipoprotein, NLP/P60 family; Identified by match to protein family HMM PF00877. (188 aa)    
Predicted Functional Partners:
AFE_1827
Membrane-bound lytic murein transglycosylase B, putative; Identified by similarity to SP:P41052.
     
 0.789
AFE_2751
Cell division protein FtsX, putative; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
 
 
 0.755
gph-1
Phosphoglycolate phosphatase; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01449; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549.
 
     0.628
ubiG
3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
       0.558
AFE_1826
Identified by match to protein family HMM PF01979; match to protein family HMM PF07969.
       0.558
ctpA
Carboxy-terminal peptidase; Identified by similarity to SP:Q44879; match to protein family HMM PF00595; match to protein family HMM PF03572; match to protein family HMM TIGR00225; Belongs to the peptidase S41A family.
    
 
 0.548
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
 
     0.535
ftsE
Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
  
 
 0.480
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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