Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_1832Hypothetical protein; Identified by glimmer; putative. (260 aa)    
Predicted Functional Partners:
AFE_1831
Hypothetical protein; Identified by glimmer; putative.
 
     0.740
AFE_1833
RNA polymerase sigm-70 factor family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
       0.714
AFE_2019
Conserved domain protein.
  
     0.663
AFE_1834
Hypothetical protein; Identified by glimmer; putative.
       0.660
rpsL
Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
    
 0.654
AFE_1830
Toluene tolerance protein, putative; Identified by similarity to GB:AAD17960.1; match to protein family HMM PF05494.
       0.604
AFE_1547
Membrane protein, putative; Identified by match to protein family HMM PF07690.
  
     0.591
tuf-2
Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
   0.517
tuf-1
Translation elongation factor Tu; Identified by similarity to SP:P48864; match to protein family HMM PF00009; match to protein family HMM PF03143; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR00485.
   
   0.517
AFE_3163
Isochorismate pyruvate lyase, putative; Identified by similarity to SP:Q51507; match to protein family HMM PF01817.
  
    0.476
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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