AFE_1848 protein (Acidithiobacillus ferrooxidans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Acidithiobacillus ferrooxidans

NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFE_1751	AFE_1848	AFE_1751	AFE_1848	umuC protein; Identified by match to protein family HMM PF00817.	Base excision repair protein, HhH-GPD family; Identified by similarity to SP:P37878; match to protein family HMM PF00730.	0.489
AFE_1751	AFE_2799	AFE_1751	AFE_2799	umuC protein; Identified by match to protein family HMM PF00817.	Transcriptional regulator, Ada family/DNA-3-methyladenine glycosylase II; Identified by similarity to SP:P04395; match to protein family HMM PF00165; match to protein family HMM PF00730; match to protein family HMM PF02805; match to protein family HMM PF06029.	0.602
AFE_1751	polI	AFE_1751	AFE_3094	umuC protein; Identified by match to protein family HMM PF00817.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.606
AFE_1846	AFE_1848	AFE_1846	AFE_1848	Hypothetical protein; Identified by glimmer; putative.	Base excision repair protein, HhH-GPD family; Identified by similarity to SP:P37878; match to protein family HMM PF00730.	0.618
AFE_1846	AFE_1850	AFE_1846	AFE_1850	Hypothetical protein; Identified by glimmer; putative.	Conserved domain protein; Identified by similarity to GB:AAP04750.1.	0.618
AFE_1848	AFE_1751	AFE_1848	AFE_1751	Base excision repair protein, HhH-GPD family; Identified by similarity to SP:P37878; match to protein family HMM PF00730.	umuC protein; Identified by match to protein family HMM PF00817.	0.489
AFE_1848	AFE_1846	AFE_1848	AFE_1846	Base excision repair protein, HhH-GPD family; Identified by similarity to SP:P37878; match to protein family HMM PF00730.	Hypothetical protein; Identified by glimmer; putative.	0.618
AFE_1848	AFE_1850	AFE_1848	AFE_1850	Base excision repair protein, HhH-GPD family; Identified by similarity to SP:P37878; match to protein family HMM PF00730.	Conserved domain protein; Identified by similarity to GB:AAP04750.1.	0.829
AFE_1848	AFE_1855	AFE_1848	AFE_1855	Base excision repair protein, HhH-GPD family; Identified by similarity to SP:P37878; match to protein family HMM PF00730.	Membrane protein, putative; Identified by match to protein family HMM PF07690.	0.560
AFE_1848	AFE_2100	AFE_1848	AFE_2100	Base excision repair protein, HhH-GPD family; Identified by similarity to SP:P37878; match to protein family HMM PF00730.	Hypothetical protein; Identified by glimmer; putative.	0.722
AFE_1848	AFE_2799	AFE_1848	AFE_2799	Base excision repair protein, HhH-GPD family; Identified by similarity to SP:P37878; match to protein family HMM PF00730.	Transcriptional regulator, Ada family/DNA-3-methyladenine glycosylase II; Identified by similarity to SP:P04395; match to protein family HMM PF00165; match to protein family HMM PF00730; match to protein family HMM PF02805; match to protein family HMM PF06029.	0.951
AFE_1848	AFE_2800	AFE_1848	AFE_2800	Base excision repair protein, HhH-GPD family; Identified by similarity to SP:P37878; match to protein family HMM PF00730.	Identified by match to protein family HMM PF00903.	0.723
AFE_1848	polI	AFE_1848	AFE_3094	Base excision repair protein, HhH-GPD family; Identified by similarity to SP:P37878; match to protein family HMM PF00730.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.537
AFE_1848	xth-1	AFE_1848	AFE_0178	Base excision repair protein, HhH-GPD family; Identified by similarity to SP:P37878; match to protein family HMM PF00730.	Exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633.	0.541
AFE_1848	xth-2	AFE_1848	AFE_0174	Base excision repair protein, HhH-GPD family; Identified by similarity to SP:P37878; match to protein family HMM PF00730.	Exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633.	0.541
AFE_1850	AFE_1846	AFE_1850	AFE_1846	Conserved domain protein; Identified by similarity to GB:AAP04750.1.	Hypothetical protein; Identified by glimmer; putative.	0.618
AFE_1850	AFE_1848	AFE_1850	AFE_1848	Conserved domain protein; Identified by similarity to GB:AAP04750.1.	Base excision repair protein, HhH-GPD family; Identified by similarity to SP:P37878; match to protein family HMM PF00730.	0.829
AFE_1855	AFE_1848	AFE_1855	AFE_1848	Membrane protein, putative; Identified by match to protein family HMM PF07690.	Base excision repair protein, HhH-GPD family; Identified by similarity to SP:P37878; match to protein family HMM PF00730.	0.560
AFE_2100	AFE_1848	AFE_2100	AFE_1848	Hypothetical protein; Identified by glimmer; putative.	Base excision repair protein, HhH-GPD family; Identified by similarity to SP:P37878; match to protein family HMM PF00730.	0.722
AFE_2100	AFE_2799	AFE_2100	AFE_2799	Hypothetical protein; Identified by glimmer; putative.	Transcriptional regulator, Ada family/DNA-3-methyladenine glycosylase II; Identified by similarity to SP:P04395; match to protein family HMM PF00165; match to protein family HMM PF00730; match to protein family HMM PF02805; match to protein family HMM PF06029.	0.722