Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
AFE_1850Conserved domain protein; Identified by similarity to GB:AAP04750.1. (77 aa)    
Predicted Functional Partners:
AFE_1848
Base excision repair protein, HhH-GPD family; Identified by similarity to SP:P37878; match to protein family HMM PF00730.
 
     0.829
AFE_2014
Alkylhydroperoxidase AhpD family core domain protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
  
     0.703
AFE_1846
Hypothetical protein; Identified by glimmer; putative.
       0.618
AFE_1845
Conserved hypothetical protein; Identified by similarity to GB:CAE32970.1.
  
     0.546
AFE_1847
C4-dicarboxylate transporter/malic acid transport protein, putative; Identified by match to protein family HMM PF03595.
 
     0.467
AFE_2993
Conserved hypothetical protein; Identified by similarity to GB:AAM36869.1.
  
     0.419
cysNC
Sulfate adenylate transferase, large subunit/adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
   
    0.416
AFE_2161
Conserved hypothetical protein; Identified by similarity to GB:AAM36869.1.
  
     0.414
AFE_2994
Conserved hypothetical protein; Identified by similarity to GB:AAM36869.1.
  
     0.413
AFE_1851
Glycosyl transferase, group 2 family protein; Identified by match to protein family HMM PF00535.
       0.403
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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