AFE_1870 protein (Acidithiobacillus ferrooxidans)

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Your Current Organism:

Acidithiobacillus ferrooxidans

NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFE_1869	AFE_1870	AFE_1869	AFE_1870	Cell division inhibitor, putative; Identified by similarity to SP:P08845.	Conserved hypothetical protein; Identified by similarity to GB:AAM40399.1.	0.923
AFE_1869	dnaE2	AFE_1869	AFE_1871	Cell division inhibitor, putative; Identified by similarity to SP:P08845.	DNA polymerase III, alpha subunit, putative; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.	0.893
AFE_1869	lexA	AFE_1869	AFE_1868	Cell division inhibitor, putative; Identified by similarity to SP:P08845.	LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.	0.955
AFE_1869	recA	AFE_1869	AFE_0932	Cell division inhibitor, putative; Identified by similarity to SP:P08845.	recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.550
AFE_1869	umuD	AFE_1869	AFE_1750	Cell division inhibitor, putative; Identified by similarity to SP:P08845.	umuD protein; Identified by similarity to SP:P04153; match to protein family HMM PF00717; Belongs to the peptidase S24 family.	0.596
AFE_1870	AFE_1869	AFE_1870	AFE_1869	Conserved hypothetical protein; Identified by similarity to GB:AAM40399.1.	Cell division inhibitor, putative; Identified by similarity to SP:P08845.	0.923
AFE_1870	AFE_2799	AFE_1870	AFE_2799	Conserved hypothetical protein; Identified by similarity to GB:AAM40399.1.	Transcriptional regulator, Ada family/DNA-3-methyladenine glycosylase II; Identified by similarity to SP:P04395; match to protein family HMM PF00165; match to protein family HMM PF00730; match to protein family HMM PF02805; match to protein family HMM PF06029.	0.602
AFE_1870	AFE_3010	AFE_1870	AFE_3010	Conserved hypothetical protein; Identified by similarity to GB:AAM40399.1.	Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.	0.540
AFE_1870	dnaE2	AFE_1870	AFE_1871	Conserved hypothetical protein; Identified by similarity to GB:AAM40399.1.	DNA polymerase III, alpha subunit, putative; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.	0.967
AFE_1870	dnaN	AFE_1870	AFE_0001	Conserved hypothetical protein; Identified by similarity to GB:AAM40399.1.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.851
AFE_1870	holB	AFE_1870	AFE_1914	Conserved hypothetical protein; Identified by similarity to GB:AAM40399.1.	DNA polymerase III, delta prime subunit; Identified by similarity to SP:P28631.	0.518
AFE_1870	lexA	AFE_1870	AFE_1868	Conserved hypothetical protein; Identified by similarity to GB:AAM40399.1.	LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.	0.834
AFE_1870	polI	AFE_1870	AFE_3094	Conserved hypothetical protein; Identified by similarity to GB:AAM40399.1.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.606
AFE_1870	recA	AFE_1870	AFE_0932	Conserved hypothetical protein; Identified by similarity to GB:AAM40399.1.	recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.662
AFE_1870	umuD	AFE_1870	AFE_1750	Conserved hypothetical protein; Identified by similarity to GB:AAM40399.1.	umuD protein; Identified by similarity to SP:P04153; match to protein family HMM PF00717; Belongs to the peptidase S24 family.	0.505
AFE_2799	AFE_1870	AFE_2799	AFE_1870	Transcriptional regulator, Ada family/DNA-3-methyladenine glycosylase II; Identified by similarity to SP:P04395; match to protein family HMM PF00165; match to protein family HMM PF00730; match to protein family HMM PF02805; match to protein family HMM PF06029.	Conserved hypothetical protein; Identified by similarity to GB:AAM40399.1.	0.602
AFE_2799	lexA	AFE_2799	AFE_1868	Transcriptional regulator, Ada family/DNA-3-methyladenine glycosylase II; Identified by similarity to SP:P04395; match to protein family HMM PF00165; match to protein family HMM PF00730; match to protein family HMM PF02805; match to protein family HMM PF06029.	LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.	0.422
AFE_2799	polI	AFE_2799	AFE_3094	Transcriptional regulator, Ada family/DNA-3-methyladenine glycosylase II; Identified by similarity to SP:P04395; match to protein family HMM PF00165; match to protein family HMM PF00730; match to protein family HMM PF02805; match to protein family HMM PF06029.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.540
AFE_2799	recA	AFE_2799	AFE_0932	Transcriptional regulator, Ada family/DNA-3-methyladenine glycosylase II; Identified by similarity to SP:P04395; match to protein family HMM PF00165; match to protein family HMM PF00730; match to protein family HMM PF02805; match to protein family HMM PF06029.	recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.628
AFE_3010	AFE_1870	AFE_3010	AFE_1870	Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.	Conserved hypothetical protein; Identified by similarity to GB:AAM40399.1.	0.540