| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AFE_1925 | AFE_1926 | AFE_1925 | AFE_1926 | CBS domain protein; Identified by match to protein family HMM PF00571. | Conserved hypothetical protein TIGR00150; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | 0.775 |
| AFE_1925 | amtB | AFE_1925 | AFE_1922 | CBS domain protein; Identified by match to protein family HMM PF00571. | Identified by match to protein family HMM PF00909. | 0.805 |
| AFE_1925 | bioA | AFE_1925 | AFE_1924 | CBS domain protein; Identified by match to protein family HMM PF00571. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Identified by similarity to SP:P53555; match to protein family HMM PF00202; match to protein family HMM TIGR00508; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.805 |
| AFE_1925 | dnaX | AFE_1925 | AFE_1919 | CBS domain protein; Identified by match to protein family HMM PF00571. | DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.566 |
| AFE_1925 | miaA | AFE_1925 | AFE_1928 | CBS domain protein; Identified by match to protein family HMM PF00571. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.746 |
| AFE_1925 | mutL | AFE_1925 | AFE_1927 | CBS domain protein; Identified by match to protein family HMM PF00571. | Mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.746 |
| AFE_1925 | nnrD | AFE_1925 | AFE_1923 | CBS domain protein; Identified by match to protein family HMM PF00571. | YjeF-related protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. | 0.784 |
| AFE_1925 | recR | AFE_1925 | AFE_1921 | CBS domain protein; Identified by match to protein family HMM PF00571. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.605 |
| AFE_1926 | AFE_1925 | AFE_1926 | AFE_1925 | Conserved hypothetical protein TIGR00150; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | CBS domain protein; Identified by match to protein family HMM PF00571. | 0.775 |
| AFE_1926 | AFE_2516 | AFE_1926 | AFE_2516 | Conserved hypothetical protein TIGR00150; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | Conserved hypothetical protein; Identified by match to protein family HMM PF00814. | 0.979 |
| AFE_1926 | amtB | AFE_1926 | AFE_1922 | Conserved hypothetical protein TIGR00150; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | Identified by match to protein family HMM PF00909. | 0.746 |
| AFE_1926 | bioA | AFE_1926 | AFE_1924 | Conserved hypothetical protein TIGR00150; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Identified by similarity to SP:P53555; match to protein family HMM PF00202; match to protein family HMM TIGR00508; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.751 |
| AFE_1926 | dnaX | AFE_1926 | AFE_1919 | Conserved hypothetical protein TIGR00150; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.693 |
| AFE_1926 | gcp | AFE_1926 | AFE_0123 | Conserved hypothetical protein TIGR00150; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.903 |
| AFE_1926 | miaA | AFE_1926 | AFE_1928 | Conserved hypothetical protein TIGR00150; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.871 |
| AFE_1926 | mutL | AFE_1926 | AFE_1927 | Conserved hypothetical protein TIGR00150; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | Mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.809 |
| AFE_1926 | nnrD | AFE_1926 | AFE_1923 | Conserved hypothetical protein TIGR00150; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | YjeF-related protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. | 0.854 |
| AFE_1926 | recR | AFE_1926 | AFE_1921 | Conserved hypothetical protein TIGR00150; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.683 |
| AFE_2516 | AFE_1926 | AFE_2516 | AFE_1926 | Conserved hypothetical protein; Identified by match to protein family HMM PF00814. | Conserved hypothetical protein TIGR00150; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | 0.979 |
| AFE_2516 | gcp | AFE_2516 | AFE_0123 | Conserved hypothetical protein; Identified by match to protein family HMM PF00814. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.935 |
