Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_1958Outer membrane protein, OMP85 family; Identified by match to protein family HMM PF01103; match to protein family HMM PF07244. (576 aa)    
Predicted Functional Partners:
AFE_1957
Conserved hypothetical protein; Identified by similarity to GB:AAN68501.1; match to protein family HMM PF04357.
 
 0.998
AFE_2831
Hypothetical protein; Identified by glimmer; putative.
 
 
 0.888
AFE_1956
Oxidoreductase, FAD-binding; Identified by match to protein family HMM PF01266.
  
    0.781
lptD
Organic solvent tolerance protein, putative; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family.
  
     0.675
lptA
Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.
  
     0.555
AFE_2830
Conserved hypothetical protein; Identified by similarity to GB:CAD85351.1.
  
     0.554
fur-2
Transcriptional regulator, Fur family; Identified by match to protein family HMM PF01475; Belongs to the Fur family.
       0.511
bamA
Outer membrane protein, OMP85 family; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
   
 0.506
AFE_1827
Membrane-bound lytic murein transglycosylase B, putative; Identified by similarity to SP:P41052.
  
     0.502
smg
Smg family protein; Belongs to the Smg family.
  
     0.427
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.