Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dacBD-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; Identified by similarity to SP:P24228; match to protein family HMM PF02113; match to protein family HMM TIGR00666. (500 aa)    
Predicted Functional Partners:
AFE_2172
Beta-lactamase; Identified by match to protein family HMM PF00144.
 
  
 0.928
AFE_2350
D-alanyl-D-alanine carboxypeptidase, putative; Identified by similarity to SP:P08506; match to protein family HMM PF00768; Belongs to the peptidase S11 family.
     
 0.909
AFE_2567
D-alanyl-D-alanine carboxypeptidase; Identified by similarity to SP:P04287; match to protein family HMM PF00768; match to protein family HMM PF07943; Belongs to the peptidase S11 family.
     
 0.909
AFE_2923
D-alanyl-D-alanine carboxypeptidase; Identified by similarity to SP:P08506; match to protein family HMM PF00768; Belongs to the peptidase S11 family.
     
 0.909
AFE_1502
Ankyrin repeat protein/rhodanese-like domain protein; Identified by match to protein family HMM PF00023; match to protein family HMM PF00581.
   
 
 0.825
AFE_1961
AmpG permease protein, putative; Identified by similarity to SP:P36670; match to protein family HMM PF07690.
 
   
 0.791
ampD
ampD protein; Identified by similarity to SP:P13016; match to protein family HMM PF01510.
      
 0.763
pilC
Type IV pilus biogenesis protein PilC; Identified by similarity to SP:P45793; match to protein family HMM PF00482.
      
 0.720
parE
DNA topoisomerase IV, subunit B; Identified by similarity to SP:P20083; match to protein family HMM PF00204; match to protein family HMM PF00986; match to protein family HMM PF02518.
      
 0.691
AFE_0569
Identified by match to protein family HMM PF03734.
 
  
  0.587
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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