STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFE_1964Fatty acid desaturase; Identified by match to protein family HMM PF00487. (374 aa)    
Predicted Functional Partners:
AFE_0139
Conserved hypothetical protein; Identified by similarity to PIR:A81668.
  
     0.692
AFE_0169
Conserved domain protein; Identified by similarity to GB:CAD74705.1.
  
     0.661
AFE_2896
Identified by match to protein family HMM PF04932.
  
     0.560
AFE_0860
Iron-sulfur cluster-binding protein/oxidoreductase, FAD/NAD-binding; Identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970.
  
  
 0.548
AFE_0435
HAD-superfamily hydrolase, subfamily IB; Identified by match to protein family HMM PF00702.
 
     0.513
AFE_0721
Conserved hypothetical protein; Identified by similarity to PIR:A97389.
  
     0.490
AFE_2325
Hypothetical protein; Identified by glimmer; putative.
  
     0.479
AFE_3010
Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.
  
 
 0.475
AFE_1347
Hypothetical protein; Identified by glimmer; putative.
  
     0.468
AFE_1963
Hypothetical protein; Identified by glimmer; putative.
       0.419
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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