STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2005Isonitrile hydratase, putative; Identified by similarity to GB:BAC41251.1; match to protein family HMM PF01965. (228 aa)    
Predicted Functional Partners:
AFE_2008
Conserved hypothetical protein; Identified by similarity to GB:AAQ59281.1.
 
     0.780
AFE_2006
Transcriptional regulator, putative; Identified by match to protein family HMM PF04299.
       0.777
AFE_2007
Conserved hypothetical protein; Identified by similarity to GB:CAD71376.1.
       0.752
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.737
AFE_2011
Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440.
 
     0.710
AFE_2004
Acetyltransferase, GNAT family; Identified by match to protein family HMM PF00583.
  
    0.615
thiJ
4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis enzyme; Identified by similarity to SP:Q46948; match to protein family HMM PF01965; match to protein family HMM TIGR01383.
  
   
 0.542
AFE_2009
Conserved domain protein; Identified by similarity to GB:AAN32872.1.
       0.531
AFE_2148
DNA-binding protein, putative; Identified by similarity to GB:AAO56394.1; match to protein family HMM PF01381; match to protein family HMM PF07883.
  
  
 0.494
AFE_0622
Conserved hypothetical protein; Identified by similarity to GB:BAC65281.1.
  
  
 0.438
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.