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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2011Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. (203 aa)    
Predicted Functional Partners:
AFE_2005
Isonitrile hydratase, putative; Identified by similarity to GB:BAC41251.1; match to protein family HMM PF01965.
 
     0.710
AFE_2012
Conserved hypothetical protein; Identified by similarity to GB:BAC68441.1.
 
     0.670
AFE_2009
Conserved domain protein; Identified by similarity to GB:AAN32872.1.
 
     0.560
AFE_0622
Conserved hypothetical protein; Identified by similarity to GB:BAC65281.1.
  
   
 0.523
AFE_2799
Transcriptional regulator, Ada family/DNA-3-methyladenine glycosylase II; Identified by similarity to SP:P04395; match to protein family HMM PF00165; match to protein family HMM PF00730; match to protein family HMM PF02805; match to protein family HMM PF06029.
  
     0.509
AFE_1206
Hypothetical protein; Identified by glimmer; putative.
  
  
 0.455
AFE_3010
Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.
     
 0.449
AFE_2013
Transcriptional regulator, MarR family; Identified by match to protein family HMM PF01047.
  
  
 0.448
AFE_0654
ABC transporter, permease protein; Identified by match to protein family HMM PF02687.
     
 0.443
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
   
    0.422
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.