AFE_2024 protein (Acidithiobacillus ferrooxidans)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Acidithiobacillus ferrooxidans

NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFE_1802	AFE_2024	AFE_1802	AFE_2024	Fructose-bisphosphate aldolase, putative; Identified by similarity to SP:P58315; match to protein family HMM PF01791.	Identified by match to protein family HMM PF00393; match to protein family HMM PF03446; match to protein family HMM PF03807; match to protein family HMM TIGR00872.	0.449
AFE_1802	AFE_2082	AFE_1802	AFE_2082	Fructose-bisphosphate aldolase, putative; Identified by similarity to SP:P58315; match to protein family HMM PF01791.	Identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02402.	0.489
AFE_1802	AFE_2083	AFE_1802	AFE_2083	Fructose-bisphosphate aldolase, putative; Identified by similarity to SP:P58315; match to protein family HMM PF01791.	Glycosyl transferase, group 1; Identified by match to protein family HMM PF00534.	0.449
AFE_1802	gpmI-1	AFE_1802	AFE_1815	Fructose-bisphosphate aldolase, putative; Identified by similarity to SP:P58315; match to protein family HMM PF01791.	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.	0.889
AFE_1802	tal	AFE_1802	AFE_0419	Fructose-bisphosphate aldolase, putative; Identified by similarity to SP:P58315; match to protein family HMM PF01791.	Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.	0.958
AFE_1802	zwf	AFE_1802	AFE_2025	Fructose-bisphosphate aldolase, putative; Identified by similarity to SP:P58315; match to protein family HMM PF01791.	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.	0.833
AFE_2024	AFE_1802	AFE_2024	AFE_1802	Identified by match to protein family HMM PF00393; match to protein family HMM PF03446; match to protein family HMM PF03807; match to protein family HMM TIGR00872.	Fructose-bisphosphate aldolase, putative; Identified by similarity to SP:P58315; match to protein family HMM PF01791.	0.449
AFE_2024	AFE_2082	AFE_2024	AFE_2082	Identified by match to protein family HMM PF00393; match to protein family HMM PF03446; match to protein family HMM PF03807; match to protein family HMM TIGR00872.	Identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02402.	0.449
AFE_2024	AFE_2083	AFE_2024	AFE_2083	Identified by match to protein family HMM PF00393; match to protein family HMM PF03446; match to protein family HMM PF03807; match to protein family HMM TIGR00872.	Glycosyl transferase, group 1; Identified by match to protein family HMM PF00534.	0.449
AFE_2024	gpmI-1	AFE_2024	AFE_1815	Identified by match to protein family HMM PF00393; match to protein family HMM PF03446; match to protein family HMM PF03807; match to protein family HMM TIGR00872.	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.	0.449
AFE_2024	pgl	AFE_2024	AFE_2833	Identified by match to protein family HMM PF00393; match to protein family HMM PF03446; match to protein family HMM PF03807; match to protein family HMM TIGR00872.	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.	0.980
AFE_2024	purT	AFE_2024	AFE_2023	Identified by match to protein family HMM PF00393; match to protein family HMM PF03446; match to protein family HMM PF03807; match to protein family HMM TIGR00872.	Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.	0.545
AFE_2024	rpe	AFE_2024	AFE_3247	Identified by match to protein family HMM PF00393; match to protein family HMM PF03446; match to protein family HMM PF03807; match to protein family HMM TIGR00872.	Ribulose-phosphate 3-epimerase; Identified by match to protein family HMM PF00834; match to protein family HMM TIGR01163; Belongs to the ribulose-phosphate 3-epimerase family.	0.910
AFE_2024	rpiA	AFE_2024	AFE_0629	Identified by match to protein family HMM PF00393; match to protein family HMM PF03446; match to protein family HMM PF03807; match to protein family HMM TIGR00872.	Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.	0.936
AFE_2024	tal	AFE_2024	AFE_0419	Identified by match to protein family HMM PF00393; match to protein family HMM PF03446; match to protein family HMM PF03807; match to protein family HMM TIGR00872.	Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.	0.556
AFE_2024	zwf	AFE_2024	AFE_2025	Identified by match to protein family HMM PF00393; match to protein family HMM PF03446; match to protein family HMM PF03807; match to protein family HMM TIGR00872.	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.	0.995
AFE_2082	AFE_1802	AFE_2082	AFE_1802	Identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02402.	Fructose-bisphosphate aldolase, putative; Identified by similarity to SP:P58315; match to protein family HMM PF01791.	0.489
AFE_2082	AFE_2024	AFE_2082	AFE_2024	Identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02402.	Identified by match to protein family HMM PF00393; match to protein family HMM PF03446; match to protein family HMM PF03807; match to protein family HMM TIGR00872.	0.449
AFE_2082	AFE_2083	AFE_2082	AFE_2083	Identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02402.	Glycosyl transferase, group 1; Identified by match to protein family HMM PF00534.	0.992
AFE_2082	gpmI-1	AFE_2082	AFE_1815	Identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02402.	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.	0.469