Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2041Membrane protein, putative. (317 aa)    
Predicted Functional Partners:
AFE_3151
Conserved hypothetical protein; Identified by similarity to GB:CAA07033.2.
  
  
 0.817
tatC
Sec-independent protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
    
 
 0.782
AFE_1722
Hypothetical protein; Identified by glimmer; putative.
   
 
 0.745
rus
Rusticyanin; Electron carrier from cytochrome c552 to the A-type oxidase.
  
  
 0.556
AFE_2021
Copper-translocating P-type ATPase; Identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525.
  
 
 0.542
AFE_2045
Outer membrane efflux protein; Identified by match to protein family HMM PF02321.
       0.500
AFE_2043
Transporter, AcrB/AcrD/AcrF family; Identified by match to protein family HMM PF00873; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
       0.497
AFE_2044
Efflux transporter, RND family, MFP subunit; Identified by match to protein family HMM TIGR01730; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.497
AFE_2046
Hypothetical protein; Identified by glimmer; putative.
       0.497
AFE_2040
TonB-dependent receptor; Identified by match to protein family HMM PF00593.
     
 0.437
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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