Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2072Conserved domain protein. (722 aa)    
Predicted Functional Partners:
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
  
  
 0.891
AFE_0738
Type IV pilus biogenesis protein PilN; Identified by match to protein family HMM PF05137.
  
  
 0.770
AFE_1915
Type IV pilus assembly protein PilZ, putative; Identified by similarity to PIR:B59241; match to protein family HMM PF07238.
  
     0.761
AFE_0018
LysM domain protein; Identified by match to protein family HMM PF01476.
  
   
 0.759
AFE_2065
CvpA family protein; Identified by similarity to SP:P08550; match to protein family HMM PF02674.
 
    0.730
AFE_1978
Identified by match to protein family HMM TIGR01352.
  
     0.723
AFE_0737
Fimbrial assembly protein PilO, putative; Identified by match to protein family HMM PF04350.
  
  
 0.720
AFE_0736
Type 4 fimbrial biogenesis protein PilP, putative; Identified by similarity to GB:AAA93089.1.
  
    0.719
AFE_0549
Conserved hypothetical protein; Identified by similarity to PIR:E82325.
  
     0.705
AFE_0168
Hypothetical protein; Identified by glimmer; putative.
  
    0.698
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.