Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
moeAMolybdopterin biosynthesis MoeA protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (413 aa)    
Predicted Functional Partners:
mobA
Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.
 0.996
moaB
Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.
 
 0.996
mobB
Molybdopterin-guanine dinucleotide biosynthesis protein B; Identified by match to protein family HMM PF03205; match to protein family HMM TIGR00176.
 
 0.994
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
 0.980
moaC
Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
 
  
 0.962
moeB
Molybdopterin biosynthesis MoeB protein; Identified by similarity to SP:P12282; match to protein family HMM PF00899; match to protein family HMM PF05237.
 
  
 0.913
moaE
Molybdopterin converting factor, subunit 2; Identified by similarity to SP:P30749; match to protein family HMM PF02391.
 
  
 0.880
AFE_1493
Molybdenum ABC transporter, periplasmic molybdate-binding protein, putative; Identified by match to protein family HMM PF01547; match to protein family HMM TIGR01256.
 
  
 0.829
rpsL
Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
 
      0.679
sreA
Sulfur reductase, molybdopterin subunit; Identified by similarity to GB:CAC86937.1; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
  
 0.580
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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