AFE_2088 protein (Acidithiobacillus ferrooxidans)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Acidithiobacillus ferrooxidans

NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFE_0697	AFE_0846	AFE_0697	AFE_0846	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Identified by similarity to SP:P72324; match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02818; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	Alcohol dehydrogenase, zinc-containing; Identified by similarity to SP:P75691; match to protein family HMM PF00107; match to protein family HMM PF08240.	0.940
AFE_0697	AFE_1742	AFE_0697	AFE_1742	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Identified by similarity to SP:P72324; match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02818; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	Aldehyde dehydrogenase (NAD) family protein; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	0.924
AFE_0697	AFE_2088	AFE_0697	AFE_2088	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Identified by similarity to SP:P72324; match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02818; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	Zinc-binding alcohol dehydrogenase family protein; Identified by match to protein family HMM PF08240; match to protein family HMM TIGR02822.	0.945
AFE_0697	AFE_2131	AFE_0697	AFE_2131	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Identified by similarity to SP:P72324; match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02818; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	Aldehyde dehydrogenase (NAD) family protein; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	0.924
AFE_0697	AFE_3010	AFE_0697	AFE_3010	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Identified by similarity to SP:P72324; match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02818; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.	0.402
AFE_0846	AFE_0697	AFE_0846	AFE_0697	Alcohol dehydrogenase, zinc-containing; Identified by similarity to SP:P75691; match to protein family HMM PF00107; match to protein family HMM PF08240.	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Identified by similarity to SP:P72324; match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02818; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	0.940
AFE_0846	AFE_1742	AFE_0846	AFE_1742	Alcohol dehydrogenase, zinc-containing; Identified by similarity to SP:P75691; match to protein family HMM PF00107; match to protein family HMM PF08240.	Aldehyde dehydrogenase (NAD) family protein; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	0.914
AFE_0846	AFE_2088	AFE_0846	AFE_2088	Alcohol dehydrogenase, zinc-containing; Identified by similarity to SP:P75691; match to protein family HMM PF00107; match to protein family HMM PF08240.	Zinc-binding alcohol dehydrogenase family protein; Identified by match to protein family HMM PF08240; match to protein family HMM TIGR02822.	0.921
AFE_0846	AFE_2131	AFE_0846	AFE_2131	Alcohol dehydrogenase, zinc-containing; Identified by similarity to SP:P75691; match to protein family HMM PF00107; match to protein family HMM PF08240.	Aldehyde dehydrogenase (NAD) family protein; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	0.914
AFE_0846	AFE_3010	AFE_0846	AFE_3010	Alcohol dehydrogenase, zinc-containing; Identified by similarity to SP:P75691; match to protein family HMM PF00107; match to protein family HMM PF08240.	Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.	0.476
AFE_0846	leuC	AFE_0846	AFE_0624	Alcohol dehydrogenase, zinc-containing; Identified by similarity to SP:P75691; match to protein family HMM PF00107; match to protein family HMM PF08240.	3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.	0.510
AFE_1742	AFE_0697	AFE_1742	AFE_0697	Aldehyde dehydrogenase (NAD) family protein; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Identified by similarity to SP:P72324; match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02818; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	0.924
AFE_1742	AFE_0846	AFE_1742	AFE_0846	Aldehyde dehydrogenase (NAD) family protein; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	Alcohol dehydrogenase, zinc-containing; Identified by similarity to SP:P75691; match to protein family HMM PF00107; match to protein family HMM PF08240.	0.914
AFE_1742	AFE_2088	AFE_1742	AFE_2088	Aldehyde dehydrogenase (NAD) family protein; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	Zinc-binding alcohol dehydrogenase family protein; Identified by match to protein family HMM PF08240; match to protein family HMM TIGR02822.	0.914
AFE_1742	AFE_2131	AFE_1742	AFE_2131	Aldehyde dehydrogenase (NAD) family protein; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	Aldehyde dehydrogenase (NAD) family protein; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	0.901
AFE_1742	AFE_3010	AFE_1742	AFE_3010	Aldehyde dehydrogenase (NAD) family protein; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.	0.768
AFE_1742	ackA	AFE_1742	AFE_1810	Aldehyde dehydrogenase (NAD) family protein; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	0.911
AFE_2086	AFE_2087	AFE_2086	AFE_2087	Heat shock protein, Hsp20 family; Identified by similarity to GB:AAC44757.1; match to protein family HMM PF00011; Belongs to the small heat shock protein (HSP20) family.	Hypothetical protein; Identified by glimmer; putative.	0.773
AFE_2086	AFE_2088	AFE_2086	AFE_2088	Heat shock protein, Hsp20 family; Identified by similarity to GB:AAC44757.1; match to protein family HMM PF00011; Belongs to the small heat shock protein (HSP20) family.	Zinc-binding alcohol dehydrogenase family protein; Identified by match to protein family HMM PF08240; match to protein family HMM TIGR02822.	0.564
AFE_2086	AFE_2089	AFE_2086	AFE_2089	Heat shock protein, Hsp20 family; Identified by similarity to GB:AAC44757.1; match to protein family HMM PF00011; Belongs to the small heat shock protein (HSP20) family.	Hypothetical protein; Identified by glimmer; putative.	0.471