STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2121Identified by match to protein family HMM PF00535; match to protein family HMM TIGR03472. (386 aa)    
Predicted Functional Partners:
AFE_2119
Conserved hypothetical protein; Identified by similarity to SP:Q8DCD5; match to protein family HMM PF04794; match to protein family HMM TIGR03473.
 
   
 0.959
AFE_2120
Radical SAM domain protein; Identified by match to protein family HMM PF04055; match to protein family HMM TIGR03471.
 
   
 0.956
AFE_2117
Membrane protein, putative; Identified by match to protein family HMM TIGR00374; match to protein family HMM TIGR03476.
 
     0.915
AFE_2116
Hypothetical protein; Identified by glimmer; putative.
 
     0.909
AFE_2122
Conserved hypothetical protein; Identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF05368; match to protein family HMM PF07993; match to protein family HMM TIGR03466.
 
 
 0.883
shc
Squalene-hopene cyclase; Identified by similarity to SP:P33990; match to protein family HMM PF00432; match to protein family HMM TIGR01507; match to protein family HMM TIGR01787.
 
     0.861
AFE_2118
Membrane protein, putative; Identified by similarity to GB:CAD85670.1; match to protein family HMM TIGR03480.
 
   
 0.856
AFE_2115
Radical SAM domain protein; Identified by match to protein family HMM PF04055; match to protein family HMM TIGR03470.
 
   
 0.830
AFE_2123
MTA/SAH nucleosidase, putative; Identified by similarity to SP:P24247; match to protein family HMM PF01048; match to protein family HMM TIGR03468.
 
     0.789
AFE_1211
TPR domain/sulfotransferase domain protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF00685; match to protein family HMM PF07719; match to protein family HMM PF07721.
  
 
 0.767
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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