Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2134Lipoprotein, putative; Identified by similarity to GB:CAD13844.1. (221 aa)    
Predicted Functional Partners:
AFE_2135
Identified by match to protein family HMM PF02470.
 
   0.987
AFE_0654
ABC transporter, permease protein; Identified by match to protein family HMM PF02687.
  
     0.588
AFE_0160
Identified by match to protein family HMM PF02470.
  
   0.581
AFE_2782
Cation efflux system protein, putative; Identified by similarity to SP:P77214.
  
     0.577
AFE_2428
Heavy metal efflux system protein, putative; Identified by similarity to SP:P77214.
  
     0.575
AFE_3127
Conserved hypothetical protein; Identified by similarity to GB:CAD16125.1; match to protein family HMM PF01903.
  
     0.566
pcm-1
protein-L-isoaspartate O-methyltransferase; Identified by similarity to SP:P24206; match to protein family HMM PF01135.
       0.523
AFE_2137
Hydrolase, isochorismatase family; Identified by match to protein family HMM PF00857.
       0.523
AFE_2138
PDZ domain protein; Identified by match to protein family HMM PF05299.
       0.523
AFE_0646
ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.
 
    0.475
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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