AFE_2137 protein (Acidithiobacillus ferrooxidans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

AFE_2137

Hydrolase, isochorismatase family; Identified by match to protein family HMM PF00857. (181 aa)

Predicted Functional Partners:

pcm-1

0.828

AFE_2138

0.808

AFE_2135

0.541

AFE_2134

0.523

nadE

0.499

AFE_3010

0.423

Your Current Organism:

Acidithiobacillus ferrooxidans

NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFE_2134	AFE_2135	AFE_2134	AFE_2135	Lipoprotein, putative; Identified by similarity to GB:CAD13844.1.	Identified by match to protein family HMM PF02470.	0.958
AFE_2134	AFE_2137	AFE_2134	AFE_2137	Lipoprotein, putative; Identified by similarity to GB:CAD13844.1.	Hydrolase, isochorismatase family; Identified by match to protein family HMM PF00857.	0.523
AFE_2134	AFE_2138	AFE_2134	AFE_2138	Lipoprotein, putative; Identified by similarity to GB:CAD13844.1.	PDZ domain protein; Identified by match to protein family HMM PF05299.	0.523
AFE_2134	pcm-1	AFE_2134	AFE_2136	Lipoprotein, putative; Identified by similarity to GB:CAD13844.1.	protein-L-isoaspartate O-methyltransferase; Identified by similarity to SP:P24206; match to protein family HMM PF01135.	0.523
AFE_2135	AFE_2134	AFE_2135	AFE_2134	Identified by match to protein family HMM PF02470.	Lipoprotein, putative; Identified by similarity to GB:CAD13844.1.	0.958
AFE_2135	AFE_2137	AFE_2135	AFE_2137	Identified by match to protein family HMM PF02470.	Hydrolase, isochorismatase family; Identified by match to protein family HMM PF00857.	0.541
AFE_2135	AFE_2138	AFE_2135	AFE_2138	Identified by match to protein family HMM PF02470.	PDZ domain protein; Identified by match to protein family HMM PF05299.	0.540
AFE_2135	pcm-1	AFE_2135	AFE_2136	Identified by match to protein family HMM PF02470.	protein-L-isoaspartate O-methyltransferase; Identified by similarity to SP:P24206; match to protein family HMM PF01135.	0.541
AFE_2137	AFE_2134	AFE_2137	AFE_2134	Hydrolase, isochorismatase family; Identified by match to protein family HMM PF00857.	Lipoprotein, putative; Identified by similarity to GB:CAD13844.1.	0.523
AFE_2137	AFE_2135	AFE_2137	AFE_2135	Hydrolase, isochorismatase family; Identified by match to protein family HMM PF00857.	Identified by match to protein family HMM PF02470.	0.541
AFE_2137	AFE_2138	AFE_2137	AFE_2138	Hydrolase, isochorismatase family; Identified by match to protein family HMM PF00857.	PDZ domain protein; Identified by match to protein family HMM PF05299.	0.808
AFE_2137	AFE_3010	AFE_2137	AFE_3010	Hydrolase, isochorismatase family; Identified by match to protein family HMM PF00857.	Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.	0.423
AFE_2137	nadE	AFE_2137	AFE_0428	Hydrolase, isochorismatase family; Identified by match to protein family HMM PF00857.	Glutamine-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.499
AFE_2137	pcm-1	AFE_2137	AFE_2136	Hydrolase, isochorismatase family; Identified by match to protein family HMM PF00857.	protein-L-isoaspartate O-methyltransferase; Identified by similarity to SP:P24206; match to protein family HMM PF01135.	0.828
AFE_2138	AFE_2134	AFE_2138	AFE_2134	PDZ domain protein; Identified by match to protein family HMM PF05299.	Lipoprotein, putative; Identified by similarity to GB:CAD13844.1.	0.523
AFE_2138	AFE_2135	AFE_2138	AFE_2135	PDZ domain protein; Identified by match to protein family HMM PF05299.	Identified by match to protein family HMM PF02470.	0.540
AFE_2138	AFE_2137	AFE_2138	AFE_2137	PDZ domain protein; Identified by match to protein family HMM PF05299.	Hydrolase, isochorismatase family; Identified by match to protein family HMM PF00857.	0.808
AFE_2138	pcm-1	AFE_2138	AFE_2136	PDZ domain protein; Identified by match to protein family HMM PF05299.	protein-L-isoaspartate O-methyltransferase; Identified by similarity to SP:P24206; match to protein family HMM PF01135.	0.808
AFE_3010	AFE_2137	AFE_3010	AFE_2137	Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.	Hydrolase, isochorismatase family; Identified by match to protein family HMM PF00857.	0.423
AFE_3010	nadE	AFE_3010	AFE_0428	Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.	Glutamine-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.564