STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2148DNA-binding protein, putative; Identified by similarity to GB:AAO56394.1; match to protein family HMM PF01381; match to protein family HMM PF07883. (181 aa)    
Predicted Functional Partners:
AFE_2287
Transcriptional regulator, GntR family; Identified by match to protein family HMM PF00392; match to protein family HMM TIGR02325.
 
  
 0.893
hyfB
Hydrogenase-4, B subunit; Identified by similarity to SP:P23482; match to protein family HMM PF00361.
       0.805
hyfC
Hydrogenase-4, C subunit; Identified by similarity to SP:P77858; match to protein family HMM PF00146.
       0.805
hyfE
Hydrogenase-4, E subunit; Identified by similarity to SP:P77524.
       0.805
hyfF
Hydrogenase-4, F subunit; Identified by similarity to SP:P77437; match to protein family HMM PF00361.
       0.805
hyfG
Hydrogenase-4, G subunit; Identified by similarity to SP:P77329; match to protein family HMM PF00329; match to protein family HMM PF00346.
  
    0.768
AFE_2528
Glutamine amidotransferase, class I; Identified by match to protein family HMM PF00117; match to protein family HMM PF07722.
 
  
 0.658
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
 
     0.655
ychF
GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
   
   0.644
hyfI
Hydrogenase-4, I subunit; Identified by similarity to SP:P77668; match to protein family HMM PF01058.
       0.640
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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