STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hyfGHydrogenase-4, G subunit; Identified by similarity to SP:P77329; match to protein family HMM PF00329; match to protein family HMM PF00346. (515 aa)    
Predicted Functional Partners:
hyfB
Hydrogenase-4, B subunit; Identified by similarity to SP:P23482; match to protein family HMM PF00361.
 
 
 0.999
hyfC
Hydrogenase-4, C subunit; Identified by similarity to SP:P77858; match to protein family HMM PF00146.
 
 0.999
hyfF
Hydrogenase-4, F subunit; Identified by similarity to SP:P77437; match to protein family HMM PF00361.
 
 
 0.999
hyfI
Hydrogenase-4, I subunit; Identified by similarity to SP:P77668; match to protein family HMM PF01058.
 
 
 0.999
hyfE
Hydrogenase-4, E subunit; Identified by similarity to SP:P77524.
 
  
 0.998
AFE_1512
Ferredoxin; Identified by similarity to SP:P46036; match to protein family HMM PF00037; match to protein family HMM TIGR02936.
  
 
 0.965
nuoI
NADH-quinone oxidoreductase, I subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
 
 0.961
nuoG
NADH-quinone oxidoreductase, G subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.
  
 
 0.948
nuoF
NADH-quinone oxidoreductase, F subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.
  
 
 0.948
AFE_1530
Ferredoxin; Identified by similarity to SP:P00207; match to protein family HMM PF00037.
  
 
 0.935
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.