Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2166Toxin secretion protein, HlyD family; Identified by similarity to SP:P22519; match to protein family HMM PF00529. (445 aa)    
Predicted Functional Partners:
AFE_2167
Toxin secretion ABC transporter, ATP-binding protein, HlyB family; Identified by similarity to SP:P22520; match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF03412.
 
 
 0.981
AFE_2693
Type I secretion system ATPase; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF03412; match to protein family HMM TIGR01846.
 
 
 0.873
AFE_2169
Outer membrane toxin secretion efflux protein, putative; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
 
 
 0.814
AFE_0654
ABC transporter, permease protein; Identified by match to protein family HMM PF02687.
  
  
 0.583
AFE_2439
Copper-translocating P-type ATPase; Identified by similarity to SP:P05425; match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525.
      
 0.460
AFE_0863
RND efflux system, drug efflux transporter, outer membrane lipoprotein; Identified by match to protein family HMM PF02321; match to protein family HMM TIGR01845.
 
 
 0.456
AFE_2165
Hypothetical protein; Identified by glimmer; putative.
       0.455
AFE_0575
Type I secretion outer membrane protein, TolC family; Identified by similarity to SP:P02930; match to protein family HMM PF02321; match to protein family HMM TIGR01844.
 
 
 0.454
AFE_1880
RND efflux system, outer membrane lipoprotein, NodT family; Identified by match to protein family HMM PF02321; match to protein family HMM TIGR01845.
 
 
 0.432
AFE_0108
RND efflux system, outer membrane lipoprotein, NodT family; Identified by match to protein family HMM PF02321; match to protein family HMM TIGR01845.
 
 
 0.431
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.