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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2169Outer membrane toxin secretion efflux protein, putative; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. (496 aa)    
Predicted Functional Partners:
AFE_1879
Efflux transporter, RND family, MFP subunit; Identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  0.938
AFE_0109
Efflux transporter, RND family, MFP subunit; Identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  0.937
AFE_0575
Type I secretion outer membrane protein, TolC family; Identified by similarity to SP:P02930; match to protein family HMM PF02321; match to protein family HMM TIGR01844.
  
  
 
0.924
AFE_1878
Transporter, AcrB/AcrD/AcrF family; Identified by match to protein family HMM PF00873; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 0.923
AFE_3265
Outer membrane efflux protein; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
  
  
 
0.920
AFE_2045
Outer membrane efflux protein; Identified by match to protein family HMM PF02321.
     
 0.900
AFE_2690
Type I secretion outer membrane protein, putative; Identified by match to protein family HMM PF02321.
     
 0.900
AFE_2166
Toxin secretion protein, HlyD family; Identified by similarity to SP:P22519; match to protein family HMM PF00529.
 
 
 0.834
AFE_2167
Toxin secretion ABC transporter, ATP-binding protein, HlyB family; Identified by similarity to SP:P22520; match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF03412.
  
  
 0.767
AFE_3264
Efflux transporter, RND family, MFP subunit; Identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
   0.589
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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