Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
nudJNUDIX hydrolase; Identified by match to protein family HMM PF00293; Belongs to the Nudix hydrolase family. NudJ subfamily. (147 aa)    
Predicted Functional Partners:
rsuA
Ribosomal small subunit pseudouridine synthase A; Identified by similarity to SP:P33918; match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; Belongs to the pseudouridine synthase RsuA family.
       0.805
AFE_2072
Conserved domain protein.
 
  
 0.661
AFE_1915
Type IV pilus assembly protein PilZ, putative; Identified by similarity to PIR:B59241; match to protein family HMM PF07238.
  
     0.634
rppH
NUDIX hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.
  
  
 0.623
AFE_2176
Peptidyl-arginine deiminase, Porphyromonas-type; Identified by match to protein family HMM PF04371; Belongs to the agmatine deiminase family.
       0.565
pepP
Xaa-Pro aminopeptidase; Identified by similarity to SP:P15034; match to protein family HMM PF00557; match to protein family HMM PF05195.
 
   
 0.565
AFE_2745
Conserved hypothetical protein; Identified by similarity to PIR:S61401.
  
     0.453
AFE_2756
Conserved hypothetical protein; Identified by similarity to PIR:F83597.
 
     0.421
AFE_3010
Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.
  
  
 0.421
AFE_0530
Carbohydrate kinase, PfkB family; Identified by match to protein family HMM PF00294.
 
   
 0.416
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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