Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sreASulfur reductase, molybdopterin subunit; Identified by similarity to GB:CAC86937.1; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (909 aa)    
Predicted Functional Partners:
sreB
Sulfur reductase, iron-sulfur binding subunit; Identified by similarity to GB:CAC86938.1; match to protein family HMM PF00037.
 
 
 0.998
sreC
Sulfur reductase, membrane subunit, putative; Identified by match to protein family HMM PF03916.
 
   
 0.986
sreD
Sulfur reductase; Identified by similarity to GB:BAC59713.1.
  
 
 0.949
AFE_2553
Pyridine nucleotide-disulfide oxidoreductase; Identified by similarity to PIR:G70335; match to protein family HMM PF00070; match to protein family HMM PF07992.
   
 
 0.679
tuf-2
Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
 
 0.669
tuf-1
Translation elongation factor Tu; Identified by similarity to SP:P48864; match to protein family HMM PF00009; match to protein family HMM PF03143; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR00485.
   
 
 0.669
moeA
Molybdopterin biosynthesis MoeA protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
  
 0.580
hoxY
[NiFe] hydrogenase, delta subunit, putative; Identified by similarity to GB:BAC00530.1; match to protein family HMM PF01058.
    
 
 0.520
nuoF
NADH-quinone oxidoreductase, F subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.
   
 
 0.514
gltB
Glutamate synthase, large subunit; Identified by similarity to SP:P09831; match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898.
  
  
 0.503
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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