Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
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[Homology]
Score
AFE_2189ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005; Belongs to the ABC transporter superfamily. (337 aa)    
Predicted Functional Partners:
AFE_2190
ABC transporter, permease protein; Identified by match to protein family HMM PF00528.
  
 0.983
AFE_1498
ABC transporter, periplasmic substrate-binding protein, putative; Identified by match to protein family HMM PF01547.
 
  
 0.865
AFE_3164
ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.
  
    0.731
apaH
Bis(5-nucleosyl)-tetraphosphatase (symmetrical); Identified by match to protein family HMM PF00149.
       0.554
rpsK
Ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
  
    0.536
AFE_2191
Hypothetical protein; Identified by glimmer; putative.
       0.535
AFE_2192
Hypothetical protein; Identified by glimmer; putative.
       0.535
rpsT
Ribosomal protein S20; Binds directly to 16S ribosomal RNA.
  
    0.511
rpsE
Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
  
     0.507
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
 
     0.438
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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